Download presentation
Presentation is loading. Please wait.
1
An Activation Marker Finds a Function
Diana M. Mitchell, Matthew A. Williams Immunity Volume 32, Issue 1, Pages 9-11 (January 2010) DOI: /j.immuni Copyright © 2010 Elsevier Inc. Terms and Conditions
2
Figure 1 CD44 Prevents Fas-Mediated Apoptosis during Th1 Cell Clonal Expansion After activation in response to influenza infection, Th1 cells upregulate CD44, overcome Fas-induced death signals, undergo clonal expansion, and populate the memory pool after pathogen clearance. In the absence of CD44 signals, clonally expanding T cells undergo Fas-mediated apoptosis and fail to progress to the memory cell pool. Immunity , 9-11DOI: ( /j.immuni ) Copyright © 2010 Elsevier Inc. Terms and Conditions
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.