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Outbreak of brainstem encephalitis associated with enterovirus-A71 in Catalonia, Spain (2016): a clinical observational study in a children's reference.

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Presentation on theme: "Outbreak of brainstem encephalitis associated with enterovirus-A71 in Catalonia, Spain (2016): a clinical observational study in a children's reference."— Presentation transcript:

1 Outbreak of brainstem encephalitis associated with enterovirus-A71 in Catalonia, Spain (2016): a clinical observational study in a children's reference centre in Catalonia  D. Casas-Alba, M.F. de Sevilla, A. Valero-Rello, C. Fortuny, J.-J. García-García, C. Ortez, J. Muchart, T. Armangué, I. Jordan, C. Luaces, I. Barrabeig, R. González-Sanz, M. Cabrerizo, C. Muñoz-Almagro, C. Launes  Clinical Microbiology and Infection  Volume 23, Issue 11, Pages (November 2017) DOI: /j.cmi Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Cases per week of EV-related neurological disease, classified according to the case definitions from the WHO Guide to Clinical Management and Public Health Response for Hand, Foot and Mouth Disease [21]. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Phylogenetic analysis of 38 Catalonian and 31 worldwide strains of EV-A71 based on a 360-nucleotide 3′-VP1 sequence. MEGA 6 software was used to construct the NJ and MCL tree. CV-A16 prototype strain G-10 was used as the outgroup. Bootstrap values >70% are indicated at the branch nodes. The Catalonian strains from 2016 are indicated by black circles. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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