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(6h ) Supplemental Fig. 2 a. 32Dp210 b. 32Dp210 c. 32DP210

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Presentation on theme: "(6h ) Supplemental Fig. 2 a. 32Dp210 b. 32Dp210 c. 32DP210"— Presentation transcript:

1 (6h ) Supplemental Fig. 2 a. 32Dp210 b. 32Dp210 c. 32DP210
C (min) pTyr 360 Bcr-Abl Grb2 WP1193 (M) WB a Dp210 WP1193 (M) Untreated Image Quant (%) Jak2 IP: Jak2 32P pJak2 (WB) b Dp210 C (min) pTyr177 Bcr-Abl pGab2 Gab2 GRB2 WP1193 (10M) (WB) c. 32DP210 C (min) pTyr177 Bcr-Abl Bcr-Abl  - Actin WP1193 (10M) (WB) d K562-R C (min) pSTAT5 (Tyr694)  - Actin (WB) WP1193 (10 M) e DP210 pBcr-Abl  - Actin anti-Abl WP1193 (M) Untreated (WB) Anti-pTyr Ab4G10 f Dp210 Imatinib (M) C P32 pBcr-Abl Bcr-Abl kinase  - Actin (Sup) anti- Abl g Dp210 pTyr177 Bcr-Abl Bcr-Abl b-Actin WP1193 (mM) C (6h ) WB h.


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