Presentation is loading. Please wait.

Presentation is loading. Please wait.

Serum Biomarkers May Prognosticate Recurrence in Node-Negative, Non-Small Cell Lung Cancers Less Than 4 Centimeters  Christopher W. Seder, MD, Andrew.

Published byNeal Singleton Modified over 6 years ago

Similar presentations

Presentation on theme: "Serum Biomarkers May Prognosticate Recurrence in Node-Negative, Non-Small Cell Lung Cancers Less Than 4 Centimeters  Christopher W. Seder, MD, Andrew."— Presentation transcript:

1 Serum Biomarkers May Prognosticate Recurrence in Node-Negative, Non-Small Cell Lung Cancers Less Than 4 Centimeters  Christopher W. Seder, MD, Andrew T. Arndt, MD, Lia Jordano, MD, Sanjib Basu, PhD, Cristina L. Fhied, MS, Selina Sayidine, MD, Gary W. Chmielewski, MD, Kelsey Gallo, BS, Michael J. Liptay, MD, Jeffrey A. Borgia, PhD  The Annals of Thoracic Surgery  Volume 104, Issue 5, Pages (November 2017) DOI: /j.athoracsur Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Univariate analysis of clinical characteristics and biomarker concentrations to prognosticate recurrence in resected, node-negative non-small cell lung cancer less than 4 cm. An odds ratio (OR) greater than 1 indicates higher probability of recurrence with increasing biomarker levels, whereas an odds ratio less than 1 indicates lower probability of recurrence with increasing biomarker levels. (AFP = alpha-fetoprotein; BMP = bone morphogenetic protein; CEA = carcinoembryonic antigen; CI = confidence interval; FGF = fibroblast growth factor; G-CSF = granulocyte colony-stimulating factor; HB-EGF = heparin-binding endothelial growth factorlike growth factor; HCG = human chorionic gonadotropin; HE = human epididymis protein; IGFBP = insulinlike growth factor–binding protein; PLGF = placental growth factor; SCF = colony-stimulating factor; TNF = tumor necrosis factor; TNFRI = tumor necrosis factor receptor I; VEGF = vascular endothelial growth factor.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Receiver-operating characteristics curves for the seven-analyte biomarker panel. Area under the curve (AUC) is 0.70, with an overall accuracy of 78%, specificity of 91%, and negative predictive value of 83%. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Download ppt "Serum Biomarkers May Prognosticate Recurrence in Node-Negative, Non-Small Cell Lung Cancers Less Than 4 Centimeters  Christopher W. Seder, MD, Andrew."

Similar presentations

Pulmonary Resection of Metastatic Sarcoma: Prognostic Factors Associated With Improved Outcomes Samuel Kim, MD, Harald C. Ott, MD, Cameron D. Wright, MD,

Pulmonary Resection of Metastatic Sarcoma: Prognostic Factors Associated With Improved Outcomes Samuel Kim, MD, Harald C. Ott, MD, Cameron D. Wright, MD,
Jeffrey M. Griffin, MD, MS, Carolyn E. Reed, MD, Chadrick E

Jeffrey M. Griffin, MD, MS, Carolyn E. Reed, MD, Chadrick E
Assessment of the Association of Bilateral Internal Thoracic Artery Skeletonization and Sternal Wound Infection After Coronary Artery Bypass Grafting 

Assessment of the Association of Bilateral Internal Thoracic Artery Skeletonization and Sternal Wound Infection After Coronary Artery Bypass Grafting 
Jeffrey L. Port, MD, Robert J. Korst, MD, Paul C. Lee, MD, Amanda L

Jeffrey L. Port, MD, Robert J. Korst, MD, Paul C. Lee, MD, Amanda L
Kaviyanka Selvasandran, MS, Georges Makhoul, MD, MS, Prashant K

Kaviyanka Selvasandran, MS, Georges Makhoul, MD, MS, Prashant K
Lymphovascular Invasion as a Prognostic Indicator in Stage I Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis  Nathan M. Mollberg, DO,

Lymphovascular Invasion as a Prognostic Indicator in Stage I Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis  Nathan M. Mollberg, DO,
A Propensity-Matched Analysis of Wedge Resection and Stereotactic Body Radiotherapy for Early Stage Lung Cancer  Jeffrey L. Port, MD, Bhupesh Parashar,

A Propensity-Matched Analysis of Wedge Resection and Stereotactic Body Radiotherapy for Early Stage Lung Cancer  Jeffrey L. Port, MD, Bhupesh Parashar,
Survival After Surgical Resection for Lung Cancer in Patients With Chronic Obstructive Pulmonary Disease  Anders Bugge, MD, May Brit Lund, MD, PhD, Cathrine.

Survival After Surgical Resection for Lung Cancer in Patients With Chronic Obstructive Pulmonary Disease  Anders Bugge, MD, May Brit Lund, MD, PhD, Cathrine.
True Negative Predictive Value of Endobronchial Ultrasound in Lung Cancer: Are We Being Conservative Enough?  Bryan A. Whitson, MD, PhD, Shawn S. Groth,

True Negative Predictive Value of Endobronchial Ultrasound in Lung Cancer: Are We Being Conservative Enough?  Bryan A. Whitson, MD, PhD, Shawn S. Groth,
Melanie Subramanian, MD, Timothy McMurry, PhD, Bryan F

Melanie Subramanian, MD, Timothy McMurry, PhD, Bryan F
The Society of Thoracic Surgeons Lung Cancer Resection Risk Model: Higher Quality Data and Superior Outcomes  Felix G. Fernandez, MD, MS, Andrzej S. Kosinski,

The Society of Thoracic Surgeons Lung Cancer Resection Risk Model: Higher Quality Data and Superior Outcomes  Felix G. Fernandez, MD, MS, Andrzej S. Kosinski,
Elliot Wakeam, MD, MPH, Meredith Giuliani, MBBS, MEd, Natasha B

Elliot Wakeam, MD, MPH, Meredith Giuliani, MBBS, MEd, Natasha B
Tumor Necrosis as a Prognostic Factor for Stage IA Non-Small Cell Lung Cancer  Seong Yong Park, MD, Hyun-Sung Lee, MD, PhD, Hee-Jin Jang, MD, Geon Kook.

Tumor Necrosis as a Prognostic Factor for Stage IA Non-Small Cell Lung Cancer  Seong Yong Park, MD, Hyun-Sung Lee, MD, PhD, Hee-Jin Jang, MD, Geon Kook.
Existing General Population Models Inaccurately Predict Lung Cancer Risk in Patients Referred for Surgical Evaluation  James M. Isbell, MD, MSCI, Stephen.

Existing General Population Models Inaccurately Predict Lung Cancer Risk in Patients Referred for Surgical Evaluation  James M. Isbell, MD, MSCI, Stephen.
Prediction of Prognosis and Surgical Indications for Pulmonary Metastasectomy From Colorectal Cancer  Toshihiko Iizasa, MD, Makoto Suzuki, MD, Shigetoshi.

Prediction of Prognosis and Surgical Indications for Pulmonary Metastasectomy From Colorectal Cancer  Toshihiko Iizasa, MD, Makoto Suzuki, MD, Shigetoshi.
Chi-Fu Jeffrey Yang, MD, Derek Y. Chan, BSE, Paul J

Chi-Fu Jeffrey Yang, MD, Derek Y. Chan, BSE, Paul J
Lisa M. Brown, MD, MAS, David T. Cooke, MD, Elizabeth A. David, MD 

Lisa M. Brown, MD, MAS, David T. Cooke, MD, Elizabeth A. David, MD 
Clinical Prognosis of Superior Versus Basal Segment Stage I Non-Small Cell Lung Cancer  Yoshinori Handa, MD, Yasuhiro Tsutani, MD, PhD, Norifumi Tsubokawa,

Clinical Prognosis of Superior Versus Basal Segment Stage I Non-Small Cell Lung Cancer  Yoshinori Handa, MD, Yasuhiro Tsutani, MD, PhD, Norifumi Tsubokawa,
Victoria Fröjd, MD, PhD, Anders Jeppsson, MD, PhD 

Victoria Fröjd, MD, PhD, Anders Jeppsson, MD, PhD 
Log Odds of Positive Lymph Nodes Predicts Survival in Patients After Resection for Esophageal Cancer  Jinlin Cao, MD, Ping Yuan, MD, Honghai Ma, MD, Peng.

Log Odds of Positive Lymph Nodes Predicts Survival in Patients After Resection for Esophageal Cancer  Jinlin Cao, MD, Ping Yuan, MD, Honghai Ma, MD, Peng.

Similar presentations

Ads by Google