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Randomized Phase II Trial of Irinotecan with Paclitaxel or Gemcitabine for Non-small Cell Lung Cancer: Association of UGT1A1*6 and UGT1A1*27 with Severe.

Published byLucía Rojas Medina Modified over 6 years ago

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Presentation on theme: "Randomized Phase II Trial of Irinotecan with Paclitaxel or Gemcitabine for Non-small Cell Lung Cancer: Association of UGT1A1*6 and UGT1A1*27 with Severe."— Presentation transcript:

1 Randomized Phase II Trial of Irinotecan with Paclitaxel or Gemcitabine for Non-small Cell Lung Cancer: Association of UGT1A1*6 and UGT1A1*27 with Severe Neutropenia  Yoichi Nakamura, MD, PhD, Hiroshi Soda, MD, PhD, Mikio Oka, MD, PhD, Akitoshi Kinoshita, MD, PhD, Minoru Fukuda, MD, PhD, Masaaki Fukuda, MD, PhD, Hiroshi Takatani, MD, PhD, Seiji Nagashima, MD, Yoshifumi Soejima, MD, PhD, Takashi Kasai, MD, PhD, Katsumi Nakatomi, MD, PhD, Noriyuki Masuda, MD, PhD, Kazuhiro Tsukamoto, MD, PhD, Shigeru Kohno, MD, PhD  Journal of Thoracic Oncology  Volume 6, Issue 1, Pages (January 2011) DOI: /JTO.0b013e318200e4e8 Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Kaplan-Meier curves for (A) progression-free survival and (B) overall survival. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e318200e4e8) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Linkage disequilibrium analysis for UGT1A1, UGT1A7, and UGT1A9 single-nucleotide polymorphisms. D′ (upper, red) and r2 (lower, blue) values are shown for each square. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e318200e4e8) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

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