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An Overview of Stem Cell Research and Regulatory Issues
Christopher R. Cogle, MD, Steven M. Guthrie, BS, Ronald C. Sanders, MD, William L. Allen, JD, Edward W. Scott, PhD, Bryon E. Petersen, PhD Mayo Clinic Proceedings Volume 78, Issue 8, Pages (August 2003) DOI: / Copyright © 2003 Mayo Foundation for Medical Education and Research Terms and Conditions
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Figure 1 Embryonic stem cell. At the time of conception, a single cell (zygote) is formed and subsequently grows into a cluster of totipotent blastomeres. Further cell division produces a hollow ball with an outer trophoectoderm, producing placenta and supporting tissues as well as an inner cell mass. Embryonic stem cells are derived from plating inner cell masses on a plastic dish and culturing them in incubation ovens. With further culturing, these pluripotent embryonic stem cells can form tissues of all 3 germ layers. CNS = central nervous system. … = other organs. Mayo Clinic Proceedings , DOI: ( / ) Copyright © 2003 Mayo Foundation for Medical Education and Research Terms and Conditions
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