1. T regulatory cells turn on T regulatory cells
by David W. Scott
Blood
Volume 114(19):
November 5, 2009
©2009 by American Society of Hematology

2. Regulatory CD4 T cells are generated in a FoxP3 transgenic mouse injected with an immunogenic FVIII vector.
Regulatory CD4 T cells are generated in a FoxP3 transgenic mouse injected with an immunogenic FVIII vector. When transferred to a naive recipient, these CD4 cells suppress the response to FVIII and generate Tregs from the host. Professional illustration by Kenneth X. Probst.
David W. Scott Blood 2009;114:
©2009 by American Society of Hematology