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DNA Structure & Chromosomes
Deoxyribonucleic Acid pp
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DNA Stores and transmits genetic information to make proteins
Made up of repeating units of nucleotides
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Location Prokaryotes: floats in cytoplasm
Eukaryotes: wrapped around proteins in the nucleus
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DNA Structure Nucleotides have three parts: Deoxyribose Sugar
Phosphate Group Base
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Complementary Base Pairing
Purine bonds to Pyrimidine A bonds to T G bonds to C
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DNA Bases Purines: Two-ringed bases Pyrimidines: One-ringed Bases
Adenine and Guanine Pyrimidines: One-ringed Bases Thymine and Cytosine
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DNA Bonds Two strands (at the bases) are held together by weak hydrogen bonds. The sugar phosphate backbone is held together by covalent bonds
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Double helix: DNA is double-stranded and coiled like a spiral staircase.
Backbone is like the railing and the bases are the steps.
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Chromosome Structure Coiled and compact DNA in nucleus
DNA wrapped tightly around proteins called histones
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Chromatids: two halves of a dividing chromosome
Chromatids joined by a centromere
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Chromosome Number Sex chromosomes: determine sex of the organism (X or Y) female: XX male: XY Autosomes: all other chromosomes All organisms have two copies that are homologous
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Haploid vs Diploid Haploid (n): only 1 set of chromosomes (n=23)
Typically gamete cells (eggs or sperm)
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Diploid (2n): having 2 sets of chromosomes (2n=46)
Morphologically similar (homologous) One set from mom and one set from dad 2 haploid cells (sperm and egg) can combine to make a diploid (zygote)
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