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Making It Personal: Neoantigen Vaccines in Metastatic Melanoma

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Presentation on theme: "Making It Personal: Neoantigen Vaccines in Metastatic Melanoma"— Presentation transcript:

1 Making It Personal: Neoantigen Vaccines in Metastatic Melanoma
Matthew D. Hellmann, Alexandra Snyder  Immunity  Volume 47, Issue 2, Pages (August 2017) DOI: /j.immuni Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Key Questions Remain
Following initial reports demonstrating safety and promising signals of efficacy for neoantigen vaccines, important questions for the field include how to expedite vaccine production for feasible administration in the context of metastatic disease; optimizing schedules, administration, and adjuvants for vaccination; exploring rational combinations with other immunotherapies; expanding clinical scenarios; and perhaps most critically, improving the understanding of what features makes an optimal neoantigen target for vaccination. Immunity  , DOI: ( /j.immuni ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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