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Pretreatment of VSV-GPΔ to form VSV-GP19K rescues infection in the α5β1-integrin-negative CHO cells.
Pretreatment of VSV-GPΔ to form VSV-GP19K rescues infection in the α5β1-integrin-negative CHO cells. VSV-GPΔ was either mock-treated (M; VSV-GPΔmock) or pretreated with thermolysin T to generate VSV-GP19k and analyzed by immunoblotting for GP1 (A) or used to infect the panel of CHO cells (B). Results shown in B are the averages from 9 experiments. Error bars indicate SEM. *, P ≤ relative to CHO K1 cells. ⋀, P ≤ 0.01 relative to CHO B2 cells. **, P ≤ 0.04 relative to mock-treated VSV-GPΔ in the same cells. Kathryn L. Schornberg et al. PNAS 2009;106:19: ©2009 by National Academy of Sciences
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