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Intravascular large B-cell lymphoma presenting as panniculitis

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Presentation on theme: "Intravascular large B-cell lymphoma presenting as panniculitis"— Presentation transcript:

1 Intravascular large B-cell lymphoma presenting as panniculitis
Corinne Maiolo, MBBS, S. Jan Ibbetson, MBBS, FRCPA, Shireen K. Sidhu, MBBS, FRCP, FACD, Daniel Kearney, MBBS, FRCPA  JAAD Case Reports  Volume 3, Issue 6, Pages (November 2017) DOI: /j.jdcr Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Intravascular B cell lymphoma. Subcutaneous nodules in the left inframammary region with overlying retiform purpura and extension across the abdomen. JAAD Case Reports 2017 3, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Scant mixed inflammatory cell infiltrate in fat lobules, comprising neutrophils and a few eosinophils, with vascular congestion with extensive fat necrosis and ghost outlines of fat cells. (Original magnification: ×200.) JAAD Case Reports 2017 3, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Intravascular B cell lymphoma. A vessel shows occlusion by a proliferation of intermediate-sized cells with scant cytoplasm and hyperchromatic and irregular nuclei. (Original magnification: ×400.) JAAD Case Reports 2017 3, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Strong CD20 positivity with weak co-expression of CD5 and a very high proliferation rate, indicating a B-cell intravascular lymphoma. (Original magnification: ×400.) JAAD Case Reports 2017 3, DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions


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