1. Hematologic System
Chapter 15

2. Definition
Hematologic System: encompasses the production of blood and the transport of blood throughout the body.

3. Fxns of Blood Blood supplies body tissues with Blood Transports
Oxygen
Nutrients
And various chemicals
Blood Transports
Waste products to organs for removal
Blood also
Plays role in endocrine and immune system

4. Structures of Blood Blood is formed in the bone marrow
Hematopoietic
To identify components
Draw blood: remove
Add anticoagulant: keeps from clotting
EDTA, heparin
Liquid portion
Serum
Plasma
Clotting proteins
Fats
Formed Elements
Erythrocytes
Reticulocyte
Macrophage
Leukocyte
Clotting Cells
Thromocyte

5. Test me: Blood Blood Smear Bone Marrow biopsy
Blood specimen on microscope slide
Bone Marrow biopsy

6. Pathology: Hematologic System
Anemia
Less than normal levels of red blood cells
Edema
Accumulation of fluid in the intercelluar space
Hemorrhage
Loss of blood (in a short period of time)
Leukemia
Elevation in the number of maligant white blood cells

7. Lymphatic System Fxns Part of the immune system
Returns excess lymph to the blood
Absorbs fats and fat soluble vitamins

8. Lymphatic Structures Lymph Fluid Lymph Vessels Lymph Nodes
Interstitial fluid
Baths and nourishes cells between organ
Lymph
Formed when interstitial fluid moves into capillaries
Brings nutrients and hormones to cells and carries waste away
Always goes towards the thoracic cavity
Lymph Vessels
Similar to veins (have valves to prevent back flow)
Lymph Nodes
Bean shaped structures
Filter Lymph (waste products etc) to remove viruses
Cells are destroyed here by B and T cells
Located throughout the body

9. Lymphatic Structures continued
Tonsils
Masses of lymphatic tissue
Protect nose and cranial (upper) throat portions
Described according to location
Spleen
Located in the cranial abdomen
Filters material from the blood
Stores red blood cells
Maintains balance of cells and plasma in the blood
Thymus
Immune fxn
Develops T cells

10. Immune System Fxn Specialized Cells
Protects the body from harmful substances
Encompasses many structures throughout the body
Specialized Cells
Lymphocyte (T and B)
White blood cell, involved in response works against antigens
Located in: spleen, thymus, bone marrow
T Lymphocytes: circulate, produced in bone marrow, Kills organisms on contact
Plasma cell / Plasmocytes
Produces and secretes specific antibody for specific antigen (foreign material)

11. Immune Response Overview

12. Pathology : Immune/Lymphatic
Allergy
Overreaction by the body to a particular anitgen
Anaphylazis
Severe response to a foreign substance
Autoimmune Disease
Body makes antibodies directed toward itself
Immunosuppression
Reduction or decrease in the state of resistance (more likely to get sick)

13. Oncology Study of tumors Tumors described by appearance
Malignant: cancerous
Metastasis: pathogenic growth in different sites of body
Benign: non- cancerous
Tumor=neoplasm: abnormal rapid growth of cells
Tumors described by appearance
Pedunculated: stalk bearing
Well-circumscribed: defined boarders
Invasive: spreading without boarders

14. Oncology Procedures: Pathology Chemotherapy Radiation Therapy
Surgical excision
Pathology
Blastoma: neoplasm of undifferentiated cells
Lymphoma: neoplasm composed of lymphoid tissue
Melanoma: neoplasm of melanin-pigmented cells
Osteosarcoma: malignant neoplasm composed of bone

15. Activities Chapter 15
Explanation of blood structures and elements Fig15-1
Diagram of lymph nodes (location) and what they are responsible for Fig 15-9
Pictorial representation of immune system response
Define terminology used when discussing the immune system pg 323