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NS5A inhibitors in the treatment of hepatitis C

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Presentation on theme: "NS5A inhibitors in the treatment of hepatitis C"— Presentation transcript:

1 NS5A inhibitors in the treatment of hepatitis C
Jean-Michel Pawlotsky  Journal of Hepatology  Volume 59, Issue 2, Pages (August 2013) DOI: /j.jhep Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

2 Fig. 1 Structural organization of HCV RNA and viral proteins. NS, non-structural; UTR, untranslated region. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

3 Fig. 2 Antiviral efficacy of ACH-3102 (second-generation NS5A inhibitor) compared with ACH-2928 and daclatasvir (first-generation NS5A inhibitors) on wild-type (parent) and mutated HCV replicons [69]. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2013 European Association for the Study of the Liver Terms and Conditions


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