1. The Immune System
Chapter 43 ~

2. PCA:
List the organs involved in the immune sytem:

3. Chapter 43 Warm-Up Define the following terms:
Pathogen
Antigen
Antibody
Allergen
Vaccine
What are lymphocytes? Where do B cells and T cells mature?

4. Ch. 43 Review Warm-Up
What is the difference between innate vs. adaptive immunity?
Contrast the functions of B cells and T cells.
How are antigens recognized by immune system cells?
What are memory cells?
How does HIV affect the immune system?

5. What you must know: Several elements of an innate immune response
The differences between B and T cells relative to their activation and actions.
How antigens are recognized by immune system cells
The differences in humoral and cell-mediated immunity
Why Helper T cells are central to immune responses

6. Types of Immunity Innate Immunity Non-specific All plants & animals
Adaptive Immunity
Pathogen-specific
Only in vertebrates
Involves B and T cells

8. Innate Immunity First defense Skin Mucous membranes
Secretions- skin and mucous membranes

9. “You men come with me, the rest of you run with mucus…”
Mucous membranes
Line digestive, respiratory and genital tracts
Low pH
lysozymes

11. Complement System

14. The Inflammatory Response
Tissue injury; release of chemical signals~ • histamine (basophils/mast cells):
• prostaglandins: increases blood flow & vessel permeability

15. Dilation and increased permeability of capillary~
chemokines: secreted by blood vessel endothelial cells mediates phagocytotic migration of WBCs

17. Lymphatic System: Consists of: Lymphatic vessels Lymph nodes Adenoids
Tonsils
Appendix
Spleen
Peyer’s patches

18. Lymphatic System: Function:
Traps foreign molecules and various substances
Returns lost fluids back to circulatory system

19. Lymphatic System: Connection with Immune System:
Foreign molecules and invaders encounter macrophages, dendritic cells, and lymphocytes which take various defense actions to activate and immune response and destroy pathogens.