1. HHV 5014 NUTRACEUTICAL FORMULATION TECHNOLOGY
TOPIC 8 : SOLID DOSAGE FORM COATING TECHNOLOGY
SUB-TOPIC : 8.1 EQUIPMENT REQUIREMENT
SIR NOOR MUHAMMAD SYAHRIN
LIANA | SYAMIMI | LUQMAN | AZALEA

2. INTRODUCTION SOLID DOSAGE FORM COATING
Unshaped (without specific shape)
Powder for external or internal use
Shaped
Tablets
Capsule
Transdermal patches
Coating is a process by which an essentially dry, outer layer of coating material is applied to the surface of a dosage form in order to confer specific benefits over uncoated variety.

3. STANDARD COATING PAN It is also known as conventional pan system.
8-60 inches in diameter
Rotated on its horizontal axis by a motor.

4. PERFORATED PAN Rotated on its horizontal axis in an enclosed housing
Perforated pan coaters are efficient drying systems with high coating capacity.
The coting solution is applied to the surface of the rotating
bed of tablets through spraying nozzles, which are present
inside drum.

5. SPRAY APPLICATION SYSTEM
There are two basic systems used to apply a finely divided (atomized) spray of coating solutions or suspensions onto tablet.
Air Less Spray System
Low Pressure Air-Atomized System

6. AIR LESS SPRAY SYSTEM
Liquid is pumped at high pressure pounds per square inch gauge(psig) , through a small orifice (.009 inch to .020 inch) in the fluid nozzle .
It caused finely divided spray.
The degree of atomization & the spray rate are controlled by Fluid pressure, orifice size and Viscosity of the liquid.

7. LOW PRESSURE AIR - ATOMIZED SYSTEM
Liquid is pumped through a somewhat large orifice (0.020 inch inch in diameter ) at relatively low pressure(5-50 psig)
Low pressure air contacts with the liquid stream at the tip of the atomizer & a finely divided spray is produced.
The degree of atomization is controlled by the fluid pressure ,fluid cap orifice ,viscosity of liquid , air pressure and air cap design.

8. Benefit tablet coating
Mask the taste or colour of drug
Control the release of the drug from the tablet.
Provide physical and chemical protection and protect the drug from gastric environment (acid resistant enteric coating).

9. Conclusion
Coating of pharmaceutical dosage forms to ensure and enhance the quality of tablet dosage form.
Safety aspects of coating in humans for health to ensure commercialization of technologies in pharmaceutical industry.