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Cell Cycle Rules Pluripotency

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Presentation on theme: "Cell Cycle Rules Pluripotency"— Presentation transcript:

1 Cell Cycle Rules Pluripotency
Ludovic Vallier  Cell Stem Cell  Volume 17, Issue 2, Pages (August 2015) DOI: /j.stem Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Cell Fate Specification Starts in the G1 Phase When hESCs Can Sense Differentiation Signals Cell fate commitment is only achieved in G2/M, when pluripotency is dissolved through cell-cycle-dependent mechanisms. Control of G2/M factors and subsequently absence of ART/ATM is necessary for this process. Cell Stem Cell  , DOI: ( /j.stem ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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