1. Today (1/21/15) Learning objectives:
Propagate mean and standard deviation of a sum of random variables.
Understand the differences in the experimental standard deviation and bias.
Be able to generate the PDF for a sum of random variables
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2. Question 2
Consider an MS experiment based on ion counting with a swept source (e.g., quadrupole). In a given sweep, a count is recorded every time one or more ions is detected in a given m/z channel, such that the measured counts will be binomially distributed.
-Derive an expression to recover the mean number of ions µ in a single sweep from the measured probability of observing a count p.
-What value of p corresponds to a mean bias of 1% from the true number of counts?
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3. Sums of random variables
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4. Sums of random variables
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5. Sums of random variables
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6. Sums of random variables
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7. Sums of random variables
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8. Sums of random variables
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9. Sums of random variables
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10. Sums of random variables
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11. Sums of random variables
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12. Sums of random variables
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13. Sums of random variables
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14. Tuesday (1/26/15) Independent reading:
3.3 – Experimental standard deviation
4.0 – The z-statistic and confidence intervals
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