1. The Patient With Difficult-to-Treat Hypercholesterolemia: Is Everything Under Control?

2. LDL-C Goals

4. Impact of Intensive Statin Therapy on Major Vascular Events

5. ENHANCE: Ezetimibe Lowers LDL-C Levels but Not Progression of Atherosclerosis

6. IMPROVE-IT: Ezetimibe/Simvastatin Combination vs Simvastatin Monotherapy

7. Coronary Drug Project: Niacin Associated With Reduction in Mortality in Men

8. AIM-HIGH: Niacin Improves Lipids but Not CV Events

10. Incidence of Muscle Adverse Effects

11. Statins in Patients With Dementia

13. ARIC: Reduced CHD Incidence in Individuals With PCSK9 Loss-of-Function Mutations

15. Horus: Atherosclerosis in Ancient Egypt

16. Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Patients With Elevated Risk (FOURIER)

17. ODYSSEY Outcomes: Phase 3 Post-ACS With SAR236553

18. REVEAL Trial

19. ACCELERATE Trial

20. Homozygous FH: Novel Treatments

21. FH

22. Thank you for participating in this activity

23. Abbreviations

24. Abbreviations (cont)

25. References

26. References (cont)

27. References (Cont)

28. References (Cont)