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Clinical correlates of Developmental Anatomy

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Presentation on theme: "Clinical correlates of Developmental Anatomy"— Presentation transcript:

1 Clinical correlates of Developmental Anatomy

2 Gametogenesis Long prophase in oogenesis NON dis junction
Abnormal gametes Abnormal Oocytes Abnormal Sperms

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4 Spermatogenesis Aspermia Oligospermia Azoospermia

5 Contraception Contraceptive pills Intra Uterine devices
Barrier contraceptives Surgical sterilization

6 Assisted reproductive techniques
Dispermy and triploidy IVF Intracytoplasmic sperm injection Cryopreservation GIFT ZIFT Surrogate mothers

7 Fertilization & cleavage
Non disjunction in early mitotic divisions of zygote Abnormal zygotes are usually missed

8 Ectopic implantation

9 Invasive Mole, Choriocarcinoma
Hyadatidiform Mole Partial Dispermy Complete Dispermic fertilization Monospermic fertilization Invasive Mole, Choriocarcinoma

10 Basis of Pregnancy Test
Syncitiotrophoblast secretes HCG Maintains corpous leuteum Basis for pregnancy test

11 Fate of primitive streak
By end of 4th week diminishes Degenerates completely Sacrococygeal teratoma

12 Teratogenesis associated with gastrulation
Chordoma Teratogenesis associated with gastrulation Highly sensitive stage Fate maps for major systems can be drawn

13 ABNORMALITIES Placenta Accreta. Placenta Percreta Placenta Previa
Site of attachement of Umbilical cord Centre (usual) Battle dore: margin

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