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Cellular reproduction & cancer
Chapters 17 & 18
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Mitosis a type of cell division for asexual reproduction
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DNA replication-the big picture
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After DNA replication. . . sister chromatids cytokinesis
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Cytokinesis in animal cells
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Sexual reproduction
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Meiosis
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Meiosis big picture: two cell divisions
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During meiosis I
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Crossing over
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After crossing over. . .
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Influences on cell division
Chemical factors Physical factors
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Chemical factors Growth factors;
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Physical factors Density-dependent inhibition Anchorage dependence
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Death is part of a cell life cycle
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What happens when the cell cycle malfunctions?
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Cancer cells are rounder / larger
Cancerous leukemia cells (L) & normal marrow cells (R)
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Cancer cells produce their own signals to divide
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Cancer cells do not display density-dependent inhibition
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Cancer cells do not display anchorage dependence
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Cancer cells can stimulate the development of blood vessels
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Cancer cells are essentially immortal
HeLa cells, 1951
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