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Mitochondrial import machinery: TOM - the translocase of

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Presentation on theme: "Mitochondrial import machinery: TOM - the translocase of"— Presentation transcript:

1 Mitochondrial import machinery: TOM - the translocase of
the outer membrane

2 Tom40 - the major translocation channel

3 The Tim23 complex - the major translocation channel
in the inner mitochondrial membrane

4 Transclocation across the inner mitochondrial membrane

5 Insertion of outer membrane proteins via TOB/SAM

6 Sorting pathways to the inner mitochondrial membrane

7 Sorting pathways to the intermembrane space

8 Mitochondria are highly dynamic and undergo constant fusion
and fission cycles

9 Mitochondria are highly dynamic
Fzo1 Mgm1 Ugo1 Dnm1

10 Mitochondrial fission and fusion machineries relies on
multiple GTPases With Ugo1 /fusion


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