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Hassane Izzedine, MD, PhD, Philippe Rouvier, MD, Gilbert Deray, MD 

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1 Endothelin Receptor Antagonism–Based Treatment for Scleroderma Renal Crisis 
Hassane Izzedine, MD, PhD, Philippe Rouvier, MD, Gilbert Deray, MD  American Journal of Kidney Diseases  Volume 62, Issue 2, Pages (August 2013) DOI: /j.ajkd Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Detection of endothelin 1 by immunoperoxidase staining of kidney tissue from (A, B) the case and (C, D) a healthy control. (A, C) Podocytes and (B, D) endothelial cells of an interlobular artery are shown, revealing cytoplasmic endothelin 1 (ET-1) in the case. Tissue was Bouin fixed and paraffin embedded; ET-1 antibody (catalog no. sc-21625; Santa Cruz Biotechnology Inc) was used at a dilution of 1/700; diaminobenzidine-based detection at pH 6). American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions


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