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Fenestrated endovascular grafting: The renal side of the story
Fady Haddad, MD, Roy K. Greenberg, MD, Esteban Walker, PhD, Joseph Nally, MD, Sean O’Neill, MD, Gail Kolin, RN, Sean P. Lyden, MD, Daniel Clair, MD, Timur Sarac, MD, Kenneth Ouriel, MD Journal of Vascular Surgery Volume 41, Issue 2, Pages (February 2005) DOI: /j.jvs Copyright © 2005 The Society for Vascular Surgery Terms and Conditions
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Fig 1 Bilateral renal access is established before complete graft deployment and removal of the delivery system. This image depicts guiding catheters into each of the single renal arteries. The guiding catheters are used as rails over which the stent graft can be completely expanded before the placement of renal stents. The stents are then introduced through the guiding catheters and deployed to the ostial renal artery diameter. The aortic portion is then flared as desired. Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions
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Fig 2 Summary of renal-related events and outcome. There are two patients within the renal occlusion group who are also present in the hemodialysis group. All patients requiring hemodialysis had baseline renal insufficiency. Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions
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Fig 3 Kaplan-Meier curves for survival in months. The top curve is for patients without renal dysfunction at baseline. The bottom curve is for patients with renal dysfunction at baseline. The total patients at risk is given at the bottom of the figure. Survival in the two groups is statistically different (P = .02). Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions
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Fig 4 A, Shown is a renal artery occlusion after placement of a fenestrated stent graft. The renal artery was initially patent but noted to be occluded during the follow-up period. Angiography confirmed the occlusion and noted only mild stent deformation (black arrow) on multiple oblique projections, which did not differ from its immediate post-implantation appearance. The boundary of the fenestration is demonstrated with white arrows. The position of the renal stent in the lower segment of the fenestration implies that the device has not moved at all in a caudal direction. In contrast, in B is shown a renal stent that has been crushed by the device, either from torque or caudal migration. Note the stent deformation that has occurred and the position of the stent with respect to the fenestration (white arrows). Its location in the uppermost portion of the fenestrated orifice implies some caudal device movement (3 mm by CT scan). The resultant renal artery stenosis was detected by duplex ultrasonography and treated with a supplemental stent that is relatively stiffer in nature (C). Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions
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Fig 5 A, The initial decrease in GFR, followed by stabilization in renal function within 6 months of the procedure, is noted in both groups of patients. This leads one to assume that there is a lack of ongoing renal insult, because there is no continued deterioration of GFR over time. When analyzed in a more specific per patient manner (B), expressed as a relative percent change in GFR over time, there is an improvement in GFR in subset of patients with renal dysfunction. This might indicate an aspect of renal recovery in these patients. C, Shown is delta % GFR over time segregated by preoperative renal artery stenosis. There is no significant difference in the change in GFR over time between the two groups. Journal of Vascular Surgery , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions
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