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Published bySylvia Hamilton Modified over 6 years ago
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A Focus on Polycythemia Vera for Nurse Practitioners and Physician Assistants
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Polycythemia Vera
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Case 1
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Initial Workup for PV
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WHO 2008 Diagnostic Criteria for PV
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Treatment Goals
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Risk Factors for Decreased Survival
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Risk Stratification for Thrombosis in PV
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Case 1 Laboratory Results
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Risk-Adapted Treatment Strategy
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Case 1 4 Years Later—Progressive Disease
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Cytoreductive Therapy
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Management of Disease Symptoms
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Management of Treatment-Related AEs
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Case 1: Follow-Up and Monitoring
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Evaluating Response to Treatment
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3-Way Communication Is the Key to Continuity of Care
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Case 1 10 Years Later—Progressive Disease
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Resistance/Intolerance to HU
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Treatment of HU-Resistant and Intolerant PV
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Ruxolitinib
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Mechanism of JAK-STAT Signaling
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Ruxolitinib Efficacy RESPONSE Trial
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Ruxolitinib Efficacy RESPONSE Trial (cont)
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Ruxolitinib Dosing for PV
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Ruxolitinib Dose Modifications
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Ruxolitinib Safety Profile
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Ruxolitinib Safety Profile Management
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Case 1 Treatment Plan
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Patient Communication and the Role of Caregivers
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Abbreviations
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Abbreviations (cont)
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