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Jeffrey R. Basford, MD, PhD, Thomas R

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1 Evaluation of healthy and diseased muscle with magnetic resonance elastography 
Jeffrey R. Basford, MD, PhD, Thomas R. Jenkyn, PhD, Kai-Nan An, PhD, Richard L. Ehman, MD, Guido Heers, MD, Kenton R. Kaufman, PhD, PE  Archives of Physical Medicine and Rehabilitation  Volume 83, Issue 11, Pages (November 2002) DOI: /apmr Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

2 Fig. 1 Subject in position before being placed in the MRI magnet bore. Note the positioning of the ankle, the testing apparatus, and the cables and pulleys that deliver dorsiflexion and plantarflexion torques. The figure inset shows the position of the electromechanical transducer over the muscle belly of the tibialis anterior. Archives of Physical Medicine and Rehabilitation  , DOI: ( /apmr ) Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

3 Fig. 2 Example of an MRE image. In this case, a shear wave is traveling through an agarose gel whose stiffness decreases from the left to the right. Note the decrease in the wavelength as the density of the medium decreases toward the right. Archives of Physical Medicine and Rehabilitation  , DOI: ( /apmr ) Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

4 Fig. 3 Shear wave wavelength (λ) versus applied torque for the tibialis anterior, soleus, and medial and lateral gastrocnemius muscles. Negative values of applied torque (ie, those to the left of the 0 torque position) imply that the subject's muscles are resisting a plantarflexion moment. Legend: □, control subjects; ▵, subjects with paraplegia; ●, subject with the residuals of childhood poliomyelitis. Archives of Physical Medicine and Rehabilitation  , DOI: ( /apmr ) Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

5 Fig. 4 Shear modulus (G) (ie, muscle stiffness) versus applied torque for the tibialis anterior, soleus, and medial and lateral gastrocnemius muscles. Negative values of applied torque (ie, to the left of the 0 torque resting values) imply that the subject's muscles are resisting a plantarflexion moment. Legend: □, control subjects; ▵, subjects with paraplegia; ●, subject with the residuals of childhood poliomyelitis. Archives of Physical Medicine and Rehabilitation  , DOI: ( /apmr ) Copyright © 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

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