1. Cell Communication (1.4) – Part 1
Pre – AP Biology
Cell Communication (1.4) – Part 1

2. Direct Contact

3. Local and Long distance communication

4. Pheromones Dog marking its presence

5. Earl Sutherland

6. Reception

7. Transduction

8. Response

9. Receptor protein and conformational shape change If a ligand sits in the binding site, the bottom segment that interacts with a G protein drops down

10. Cell Communication (1.4) – Part 2
Pre – AP Biology
Cell Communication (1.4) – Part 2

11. G protein communication Please look again at the previous slide

12. Tyrosine – Kinase Receptor

13. Intracellular receptor protein

14. Cascades

15. Cascades and amplification of signals

17. Know This! Sequence of Signal Transduction Response
Ligand binds with receptor protein
Conformational shape change occurs
A cascade of events amplifies and changes the signal
Activation, by phosphorylation, of a transcription enzyme
Cellular process of transcription is carried out within cell