1. Dipyrrinone Binding Studies in CDCl3
Pyrrole Amides and Their Use as Building Blocks
for the Preparation of Anion Receptors
Michael T. Huggins
We have successfully developed
a versatile method for the
preparation of a wide array of
pyrrole amides using the synthetic scheme shown. In addition, control binding studies on an unsubstituted dipyrrinone analogs have been conducted. Additional derivatives will be prepared and studied for the effectiveness at binding various anionic guests.
Dipyrrinone Binding Studies in CDCl3
GUEST
Ka1
Br-
< 10 M-1
Cl-
122 M-1
NO3-
94 M-1
HSO4-
1673 M-1
C6H5CO2H
1280 M-1
KDimerization =3850 M-1
All anions used as their respective tetrabutylammonium salts.