1. Managing Depression in Bipolar I Disorder

4. Bipolar Depression

5. DSM-5 Criteria for Bipolar I: Changes

6. “Mixed Features” Specifier

7. Patient’s Description vs “Symptoms”

8. Historical Perspective on Treatment

9. FDA-Approved Medications for Bipolar Depression

10. OFC in BP I Depression

11. Quetiapine for BP I Depression: BOLDER Ia and BOLDER IIb

12. Quetiapine: Adverse Effects

13. Lurasidone Mono- and Adjunctive Therapy for BP I Depression

14. Lurasidone: Adverse Effects

15. Comparative Efficacy

16. Treatment-Emergent Adverse Effects

17. Other Treatments for BP I Depression

18. Real World Algorithms

19. Psychosocial Therapies

20. Abbreviations

21. References

22. References (cont)

23. References (cont)