1. By Michael Fraczek and Caden Boyer
SNPs
By Michael Fraczek and Caden Boyer

2. What is it? The Video “Single Nucleotide Polymorphisms” or SNPs
Single nucleotide change in genetic code
To be “SNPs”, 2 or more versions of genetic differences present in 1% of population
Each “SNP” site has 4 possible versions (A, C, G & T)
Occur roughly every 300 nucleotides; 10 million SNPs total present in human genome

3. Basic Mechanics Two main types of SNPs: Linked SNPs and Causative SNPs
Linked SNPs do not affect protein production
Still affects drug and environmental responses
Two types of Causative SNPs: Non-coding and Coding
Coding SNPs change amino acid sequences
Non-coding SNPs change the timing or location of proteins
“Haplotype” - a combination of SNPs found on alleles in a region of DNA that are inherited from each parent

4. Applications? SNPs Profile for Drug Effectiveness
SNP microarrays for Cancer Research
Risk assessment of cancer cells
Investigating allelic association of cancers
Identification of cancer predisposition and tumor suppressor genes, as well as oncogenes
Use as a biological marker
Plant genotyping
Pacific Salmon
Determining response to environmental factors
Identifying harmful mutations
Risk assessment - genome copy number changes in cancer cells, etc.
Plant genotyping - SNPs found in maize
Environmental factors - determining individual response to environmental factors like toxins

5. Article - Alaska Department of Fish and Game
The Article

6. Sources https://ghr.nlm.nih.gov/primer/genomicresearch/snp
ith.pdf

7. Explaining Video
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2nd Video
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3rd Video