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Benefit of ELISpot in early diagnosis of tuberculous meningoencephalitis: Case report and literature review  Josefine Blume, Josef Köstler, Robert Weissert 

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Presentation on theme: "Benefit of ELISpot in early diagnosis of tuberculous meningoencephalitis: Case report and literature review  Josefine Blume, Josef Köstler, Robert Weissert "— Presentation transcript:

1 Benefit of ELISpot in early diagnosis of tuberculous meningoencephalitis: Case report and literature review  Josefine Blume, Josef Köstler, Robert Weissert  eNeurologicalSci   Volume 1, Issue 3, Pages (September 2015) DOI: /j.ensci Copyright © 2015 The Authors Terms and Conditions

2 Fig. 1 Cerebral MRI at onset of neurological symptoms (A) and after two weeks of therapy with anti-mycobacterial agents (B) in axial fluid-attenuated inversion recovery (FLAIR) images. (C) ELISpot for detection of immune reactivity against mycobacterial antigens with lymphocytes from blood and CSF of a patient with tuberculous meningoencephalitis. Number of spots indicating T lymphocytes that have secreted IFN-γ in response to the mycobacterial antigens, ESAT-6 or/and CFP-10, as well as to the mitogen phytohemagglutinin (PHA) from blood and CSF are shown. TNTC indicates too numerous to count. eNeurologicalSci  2015 1, 51-53DOI: ( /j.ensci ) Copyright © 2015 The Authors Terms and Conditions

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