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Assessing the State of Statin Therapy

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Presentation on theme: "Assessing the State of Statin Therapy"— Presentation transcript:

1 Assessing the State of Statin Therapy

2

3 Goals

4 Multiple Challenges in Statin Selection

5 Risk Factors That Potentiate Atherogenesis

6 Proportion of US Adults at Recommended Lipid Levels in NHANES

7 2013 ACC/AHA Cholesterol Guidelines 4 Statin Benefit Groups Identified

8 Certain Statins Increase the Risk of New-Onset T2D

9 JUPITER: Rosuvastatin Therapy and T2D Risk

10 T2D Due to Statins -- Rare but Real

11 Must Know -- Then Do

12 Selected Drug Interactions That Increase Statin Levels

13 Selected Statin-Drug Interaction Dosing Adjustments

14 Selected Statin-Drug Interaction Dosing Adjustments (cont)

15 Statin-Associated Myopathy Risk Factors and CYP Associations

16 Grapefruit Juice and Cranberry Juice

17 Statins and Elderly Patients Who to Treat?

18 Polypharmacy

19 PROSPER Summary

20 HIV Infection and CV Risk

21 Arterial Inflammation Linked to Immune Activation in HIV Infection

22 REPRIEVE Trial Design

23 REPRIEVE Trial Hypotheses

24 Current Challenges in Preventing and Treating CHD in HIV Infection

25 Abbreviations


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