1. Relief of Incident Dyspnea in Palliative Cancer Patients: A Pilot, Randomized, Controlled Trial Comparing Nebulized Hydromorphone, Systemic Hydromorphone, and Nebulized Saline 
Margaret A. Charles, PhD, Liz Reymond, MBBS(Hons), PhD, FAChPM, Fiona Israel, MCouns 
Journal of Pain and Symptom Management 
Volume 36, Issue 1, Pages (July 2008)
DOI: /j.jpainsymman
Copyright © 2008 U.S. Cancer Pain Relief Committee Terms and Conditions

2. Fig. 1
Flow of patients through the study. NH-nebulized hydromorphone; SH-systemic hydromorphone; NS-nebulized saline.
Journal of Pain and Symptom Management  , 29-38DOI: ( /j.jpainsymman )
Copyright © 2008 U.S. Cancer Pain Relief Committee Terms and Conditions

3. Fig. 2
Mean breathlessness with treatments: NH=nebulized hydromorphone, SH=systemic hydromorphone, NS=nebulized saline.
Journal of Pain and Symptom Management  , 29-38DOI: ( /j.jpainsymman )
Copyright © 2008 U.S. Cancer Pain Relief Committee Terms and Conditions

4. Fig. 3
(a) Respiratory rate, (b) pulse rate, (c) peripheral oxygen saturation. Objective indicators of respiratory status across treatments and time periods. NH=nebulized hydromorphone, SH=systemic hydromorphone, NS=nebulized saline.
Journal of Pain and Symptom Management  , 29-38DOI: ( /j.jpainsymman )
Copyright © 2008 U.S. Cancer Pain Relief Committee Terms and Conditions