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Volume 68, Issue 4, Pages (October 2015)

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Presentation on theme: "Volume 68, Issue 4, Pages (October 2015)"— Presentation transcript:

1 Volume 68, Issue 4, Pages 683-691 (October 2015)
A Systematic Review of Hypofractionation for Primary Management of Prostate Cancer  Bridget F. Koontz, Alberto Bossi, Cesare Cozzarini, Thomas Wiegel, Anthony D’Amico  European Urology  Volume 68, Issue 4, Pages (October 2015) DOI: /j.eururo Copyright © 2014 European Association of Urology Terms and Conditions

2 Fig. 1 Preferred Reporting Items for Systematic Reviews and Meta-analysis selection of studies included in review. BT=brachytherapy; EBRT=external-beam radiation therapy; Hypofx=hypofractionation; SIB=simultaneous integrated boost. European Urology  , DOI: ( /j.eururo ) Copyright © 2014 European Association of Urology Terms and Conditions

3 Fig. 2 Relationship between biologically equivalent dose (calculated to be equivalent in 2-Gy fractions using an α/β of 1.5Gy) and biochemical outcome for both arms of the six randomized phase 3 studies of moderate hypofractionation and standard fractionation. European Urology  , DOI: ( /j.eururo ) Copyright © 2014 European Association of Urology Terms and Conditions

4 Fig. 3 Late genitourinary and gastrointestinal toxicity for extreme hypofractionation to the intact prostate, using estimated biologically equivalent dose (calculated to be equivalent in 2-Gy fractions using an α/β of 1.5Gy). European Urology  , DOI: ( /j.eururo ) Copyright © 2014 European Association of Urology Terms and Conditions


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