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Outcome analysis in Crohn’s disease using endomicroscopy: How important and reliable is in vivo analysis of microscopic changes?  Ralf Kiesslich, MD,

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Presentation on theme: "Outcome analysis in Crohn’s disease using endomicroscopy: How important and reliable is in vivo analysis of microscopic changes?  Ralf Kiesslich, MD,"— Presentation transcript:

1 Outcome analysis in Crohn’s disease using endomicroscopy: How important and reliable is in vivo analysis of microscopic changes?  Ralf Kiesslich, MD, PhD  Gastrointestinal Endoscopy  Volume 87, Issue 6, Pages (June 2018) DOI: /j.gie Copyright © Terms and Conditions

2 Figure 1 Endomicroscopic views of impaired intestinal barrier function. A, Normal colonic crypt architecture: lumen of colonic crypts remains dark (arrow). B, Fluorescein leakage within colonic crypts (arrow) and visible irregular crypt architecture. C, Normal villi architecture in the terminal ileum. Single villi with vessels and epithelial border can be readily seen. The lumen remains dark (arrow). D, Fluorescein leakage due to higher permeability of the epithelial cell layer. The lumen becomes bright (arrow). Gastrointestinal Endoscopy  , DOI: ( /j.gie ) Copyright © Terms and Conditions


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