1. Change in mean serum creatinine, PAC-guided vs empiric therapy
Time frame
Clinically guided therapy
PAC-guided therapy p
From baseline to discharge (mg/dL)
+0.14
-0.01
0.02
From baseline to hospital day 7 (mg/dL)
+0.11
+0.02
0.01
PAC=pulmonary-artery catheter
Nohria A et al. Heart Failure Society of America 2005 Annual Scientific Meeting; September 18-21, 2005; Boca Raton, FL.

2. Drug use, PAC-guided vs empiric therapy
Drug class
Clinically guided therapy (%)
PAC-guided therapy (%) p
Vasodilators, in-hospital (%) 20 39
<0.0001
Thiazide diuretics, in-hospital (%) 34 24
0.02
Loop diuretics, in-hospital (%) 99 NS
Loop diuretics, mean discharge dosage levels (mg/d)
180
138
0.01
PAC=pulmonary-artery catheter
Nohria A et al. Heart Failure Society of America 2005 Annual Scientific Meeting; September 18-21, 2005; Boca Raton, FL.