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Endocrine System
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Endocrine: Ductless Glands that secret hormones into the body
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Functions Maintains homeostasis
Long-term control using chemical signals. The endocrine system works in parallel with the nervous system to control growth and maturation along with homeostasis.
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Hormones Chemical Messengers
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Delivery System
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Endocrine Gland Stimuli
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Grouped into three classes based on their structure:
Steroids Peptides Amines
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Steroids Progesterone Aldosterone
Made of Lipids derived from cholesterol. 2. Steroid hormones are secreted by the gonads, adrenal cortex, and placenta. Examples: Testosterone Progesterone Aldosterone
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Peptides Short chains of Amino Acids Most hormones are peptides
Processed by the E.R. and Golgi Apparatus Stored in vesicles- released when needed
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Amines A modified amino acid- tyrosine Stored in the cytoplasm
Example: epinephrine
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Lipid Soluble: Such as Steroids
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Hormones Regulate Gene Expression
First Messenger Second Messenger Regulates Gene Expression
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Water Soluble- 2 messenger mechanism
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Hypothalamus: Master Gland
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Posterior Pituitary storage of hormones produced in hypothalamus
Release upon neural impulse Diabetes insipidus- ADH deficiency – large amount of urine output
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Anterior Pituitary Gland
Produce and storage of hormones Production regulated by Hypothalamic hormones- GHRH, GHIH, TRH, CRH, GnRH, PIH
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Regulation of Ant Pit. Hormones
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Thyroid Hormone
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Negative Feedback Regulation
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Insulin and Glucagon- Regulation of Blood Sugar Levels
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Regulation of Blood Volume and Pressure
Antidiuretic hormone (ADH) is a chemical messenger molecule which is made in the hypothalamus and stored in the posterior pituitary gland. When osmoreceptors in the posterior pituitary sense blood which is too concentrated, ADH is released to increase water reabsorption by the kidneys. Review the maintenance of water and salt balance by means of antidiuretic hormone (ADH) and aldosterone on pages 318 and 323, Construct feedback loop diagrams which illustrate the regulation of: 1. Water balance in the blood by ADH. 2. Salt balance in the blood by aldosterone.
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Hormones You Need to Know
Growth Hormone Thyroid Stimulating Hormone ACTH FSH and LH ADH and Aldesterone Thyroid Hormone PTH Glucagon Calcitonin Know: Name Where Produced Target Organ Effects
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