1. Pharmacology in Drug Discovery Antagonism and course revision
Terry Kenakin Ph.D., Dept Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC
Antagonism and course revision
May 30th -31st (2016).
Salle M415, Pavillon Roger Gaudry,
Université de Montréal, 2900 Boulevard Edouard-Montpetit
Outline  
May 30th, 9 am-12:00 pm; Salle M415 General concepts of drug antagonism / orthosteric antagonism / competitive vs non-competitive antagonism / antagonist hemi-equilibria
May 30th, 1:30-4 pm; Salle M415/
Partial agonism / inverse agonism / therapeutic applications of inverse agonism / in vivo antagonism (target coverage), Safety Pharmacology
May 31st, 9 am-12:00 pm; Salle M415
Drug Development: ADME properties I: (Absorption, Distribution, Metabolism, Excretion)
May 30th, 1:30-3:30 pm
Drug Development: ADME properties II: (Metabolism, Excretion) / Whole Course Review