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HISTOLOGY OF CARDIAC MUSCLE & HEART
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CIRCULATORY SYSTEM COMPONENTS BLOOD VASCULAR SYSTEM
LYMPH VASCULAR SYSTEM COMPONENTS HEART ARTERIES CAPILLARIES VEINS LYMPHATIC CAPILLARIES LYMPH VESSELS LYMPHOID ORGANS
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General Plan of Vessels
Endothelium (Tunica Intima) Muscular tissue (Tunica Media) Connective tissue (Tunica Adventitia)
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HEART Modified blood vessel ENDOCARDIUM: Simple squamous epithelium
Sub endothelial connective tissue Sub endocardial connective tissue ( veins, purkinje fibers, arteries) Valves MYOCARDIUM: Thickest layer of cardiac muscles Arrangement EPICARDIUM: Loose connective tissue ( veins, nerves, ganglia) Mesothelium (visceral pericardium)
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Heart Valves
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CARDIAC MUSCLE
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Cardiac Muscle
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Atrial Muscle
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Ischemia Regenerative capability Mesenchymal stem cell potential
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INTERCALATED DISCS Junctional complexes at interface of adjacent cells
Step like appearance Transverse portion Vertical portion Junctional specializations Fascia adherentes: (anchoring sites for actin) Macula adherentes: (desmosomes) Gap junctiona: in lateral portion
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T- TUBULES & SARCOPLASMIC RETICULUM
Less regular arrangement T- Tubules are more numerous At level of Z- line DIAD CONDUCTING SYSTEM Mitochondria more numerous Lipofuscin pigment granules
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CARDIAC FIBROUS SKELETON
Septum membranaceum Trigona fibrosa Annuli fibrosa Composed of dense connective tissue CONDUCTING SYSTEM
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