1. A Stepping Stone Toward Personalized Oncology: Genomic Analysis of Circulating Tumor Cells to Guide Management of Metastatic Castration-resistant Prostate Cancer 
Archana Anantharaman, Terence W. Friedlander 
European Urology 
Volume 68, Issue 6, Pages (December 2015)
DOI: /j.eururo
Copyright © 2015 European Association of Urology Terms and Conditions

2. Fig. 1
Representation of splicing of androgen receptor (AR) to full length, wild-type AR versus truncated, constitutively active splice variant AR-V7. Absence of LBD in AR-V7 prevents activity of available AR targeted agents.
AA=antiandrogen therapy (eg, bicalutamide, nilutamide, flutamide, enzalutamide); AR=androgen receptor; DBD=DNA binding domain; DHT=dihydrotestosterone; LBD=ligand binding domain; NTD=N-terminal domain.
European Urology  , DOI: ( /j.eururo )
Copyright © 2015 European Association of Urology Terms and Conditions