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Expert Perspectives on HSCT: Planning for Success
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Learning Objectives
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Overview
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Mobilization of Stem Cells
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Bone Marrow vs Peripheral Blood Stem Cells
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Mobilizing With GM-CSF and G-CSF
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Strategies for Avoiding Mobilization Failure
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Conditioning Regimens
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Factors to Consider When Selecting a Conditioning Regimen
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Comparing Outcomes of Myeloablative vs Nonmyeloablative Conditioning
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The Effects of Dose Intensity
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Pharmacokinetic Sampling
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An Alternative View
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CIBMTR Study of Outcomes of Full-Intensity and RIC Regimens
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Preventing Relapse
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Serotherapy
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Preventing GVHD: T-Cell Depletion
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Preventing GVHD: T-Cell Depletion (cont)
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Newer Pharmacologic Options For Preventing GVHD
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Preventing Post-Transplant Infections
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A Challenging Case
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What Role Should TBI Have?
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Conclusions
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Abbreviations
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Abbreviations (cont)
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References
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References (cont)
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References (cont)
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References (cont)
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References (cont)
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References (cont)
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References (cont)
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