1. Pneumococcal Disease Prevention in Children: Issues in the Era of PCVs

3. Effect of PCV Use on IPD in Children

4. Effect of PCV Use on IPD in Adults

5. Composition of PCVs

6. The Importance of Targeting Additional Serotypes With PCV13

7. Effect of PCV13 Use on Serotype Distribution in the United States

8. Effect of PCV10 Use on Serotype Distribution in Iceland

9. Herd Effect: PCV Use and Serotype Distribution in Adults

10. Herd Effect: PCV Use and Pneumonia in Adults

11. Herd Effect: PCV Use and Nasopharyngeal Carriage in Unvaccinated Children

12. Herd Effect: PCV Use and IPD

13. Herd Effect: Haemophilus Influenzae Vaccination

14. Reducing Nasopharyngeal Carriage: Effect of PCV10 Use Across All Age Groups

15. Reducing Nasopharyngeal Carriage: Effect on Serotype Prevalence

16. Serotype Replacement: PCV7 Use and Otitis Media

17. Serotype Replacement: High-Valent PCV Use and IPD in Germany

18. Serotype Replacement: Effect of PCV Use on Carriage Rates and IPD Incidence in Iceland

19. Invasiveness of Nonvaccine Serotypes

20. PCV Use and Antibiotic-Nonsusceptible Serotypes

21. PCV Use and Antibiotic Usage

22. Looking Ahead: Improving Effectiveness Against Virulent Pneumococci

23. PCV10 vs PCV13: Optimizing Clinical Use

24. Conclusions

25. Abbreviations