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Shawn A. Schreiner, M. D. , Brian Gorman, M. B. B. Ch. , M. B. A

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Presentation on theme: "Shawn A. Schreiner, M. D. , Brian Gorman, M. B. B. Ch. , M. B. A"— Presentation transcript:

1 Chemotherapy-Related Hepatotoxicity Causing Imaging Findings Resembling Cirrhosis 
Shawn A. Schreiner, M.D., Brian Gorman, M.B.B.Ch., M.B.A., David H. Stephens, M.D.  Mayo Clinic Proceedings  Volume 73, Issue 8, Pages (August 1998) DOI: / Copyright © 1998 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Fig. 1 (case 1). A, Contrast-enhanced computed tomographic scan of abdomen, showing inhomogeneity of liver, but no discrete mass is evident. Caudate lobe is substantially enlarged. B, Tl-weighted (repetition time, 250 ms; echo time, 14 ms) magnetic resonance image (MRI), showing several slightly hyperintense areas (arrows). C, T2-weighted (repetition time, 2,500 ms; echo time, 60 ms with fat saturation) MRI, showing that hyperintense areas seen on Tl-weighted sequence are of low signal intensity, characteristic of regenerative nodules. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 1998 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Fig. 2 (case 2). A, Longitudinal ultrasound study of liver, showing rnultiple hypoechoic solid masses (arrows) that have appearance of metastases. RK - right kidney. B, Contrast-enhanced computed tomographic scan, demonstrating nodular contour to liver, but no discrete masses are evident. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 1998 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Fig. 3 (case 3). Contrast-enhanced computed tomographic (CT) scans of liver. A, Scan obtained on Oct. 22, 1996, showing multiple metastases throughout liver (arrows). B, Scan obtained on Dec. 13, 1996, demonstraling that metastatic lesions noted on earlier CT scan have regressed. Note linear areas of diminished attenuation in liver and irregularity of its surface. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 1998 Mayo Foundation for Medical Education and Research Terms and Conditions


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