1. Cyberinfrastructure for the Life Sciences
(and beyond)
PI: Parker Antin, University of Arizona
Professor of Cellular and Molecular Medicine
Associate Dean for Research of the College of Agriculture and Life Sciences
Eric Lyons
Nirav Merchant
Matthew Vaughn
Doreen Ware
David Micklos
Ann Stapleton
Karen Cone, Program Director
National Science Foundation
September 2016

2. CyVerse is a Cyberinfrastructure
Vision: Transforming science through data-driven discovery
Mission: To design, develop, deploy, and expand a national cyberinfrastructure for life science research, and to train scientists in its use 2

3. National Science Foundation Biological Sciences Directorate
CyVerse is funded by
National Science Foundation
Biological Sciences Directorate
Division of Biological Infrastructure
$100 Million, 10-year investment
CyVerse resources are:
Freely available to the community
Intended to spur national and international collaboration for research and education
DBI and DBI 3

4. The Evolution of CyVerse
From plant science, to life science, and beyond…
iPlant 2008
Empowering a
New Plant Biology
iPlant 2013
Cyberinfrastructure for
Life Science
CyVerse 2016
Transforming Science Through Data-Driven Discovery 4

5. CyVerse supports all domains of life science
Plant / Microbial Animal Biomedical Ecological/Climate
…by providing powerful computational infrastructure to handle huge datasets and complex analyses
Platforms, tools, datasets
Storage and compute
Training and support 5

6. CyVerse Supports Users at All Levels
User perspectives and potential applications
Bench Scientist
Bioinformatician
Core Facilities
Welch et al. 2013 6

7. CyVerse Cyberinfrastructure: Architecture and Products
Federated Storage
National CI
Virtualization
Job
Scheduling
Single
Sign-on
Science
platforms
Domain-specific services
Established
software and CI
Hardware resources
Ease of Use 7

8. Products Overview 8 Atmosphere
User-provisioned, highly configurable cloud computing environment tailored for life sciences
Discovery Environment
Web-accessible analysis workbench and gateway to national HPC infrastructure (XSEDE)
Bisque
Software for managing, analyzing and visualizing high throughput imaging data
Data Store
Scalable data storage for managing and sharing data across CyVerse’s CI and external data resources
Science APIs
Automation interfaces to connect data and computation for rapid integration with external resources. Also used as a graduate teaching platform.
DNA Subway
Classroom-friendly bioinformatics teaching platform
Powered by CyVerse
Third-party applications built on CyVerse’s foundational services and infrastructure 8

9. How CyVerse is Being Used
Build new systems -- Powered by CyVerse components, but managed by the builders
Consume specific components (a la carte, Data Store, Atmosphere, Bisque)
Directly use applications (Discovery Environment)
Custom design appliances (Atmosphere)
Publish findings and data
Create learning materials and courses
Advocate use 9

10. CyVerse: Reference CI Model Transforming Research in All Disciplines
Physical Sciences
Plant Sciences
Science
platforms
and
Domain-specific services
Animal Sciences
Increased disciplinary emphasis
Increased interdisciplinary sharing
Established
software and CI
Federated Storage
Job
Scheduling
Single
Sign-on
National CI
Virtualization
Hardware resources 10

11. CyVerse: Hub of a Growing CI Ecosystem
Plant genomics, phenomics, and systems biology
Bovine genomics
Biological
Sciences
Marine virus metagenomics
Immunology research data
Earthquake, wind and water hazards modeling
Physical
Sciences
Astronomy data curation and management 11

12. Summary
CyVerse is a data-to-discovery cyberinfrastructre platform that is transforming life science research
CyVerse is a reference model for cyberinfrastructure
Extensible to other disciplines
Scalable for big data analysis 12