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Mesothelium regeneration on acellular bovine pericardia loaded with an angiogenic agent (ginsenoside Rg1) successfully reduces postsurgical pericardial.

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Presentation on theme: "Mesothelium regeneration on acellular bovine pericardia loaded with an angiogenic agent (ginsenoside Rg1) successfully reduces postsurgical pericardial."— Presentation transcript:

1 Mesothelium regeneration on acellular bovine pericardia loaded with an angiogenic agent (ginsenoside Rg1) successfully reduces postsurgical pericardial adhesions  Yen Chang, MD, Po-Hong Lai, MS, Chung-Chi Wang, MD, Sung-Ching Chen, PhD, Wei-Chun Chang, MS, Hsing-Wen Sung, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 132, Issue 4, Pages e3 (October 2006) DOI: /j.jtcvs Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Photographs of the e-PTFE, cellular, acellular, and acellular/Rg1 patches (marked by * at one of the corners of each implanted patch) retrieved at 3 months after surgery. Arrows point to the sites of pericardial adhesions. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Photomicrographs (stained with hematoxylin and eosin; original magnification, 200×) of the e-PTFE, Cellular, Acellular, and Acellular/Rg1 patches retrieved at 3 months after surgery. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Photomicrographs of the acellular and acellular/Rg1 patches retrieved at 3 months after surgery: immunohistochemical stains identified neocollagen type III (brown staining; original magnification, 800×); van Gieson stain identified mesothelial cells (original magnification, 800×). The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

5 Figure E1 Photomicrographs (stained with hematoxylin and eosin [H&E]; original magnification, 200×) and scanning electron micrographs (SEM) of the Cellular and Acellular patches used in the study. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

6 Figure E2 Photomicrographs (stained with hematoxylin and eosin; original magnification, 200×) of the e-PTFE, Cellular, Acellular, and Acellular/Rg1 patches retrieved at 1 month after surgery. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

7 Figure E3 Photomicrographs of the Acellular and Acellular/Rg1 patches retrieved at 3 months after surgery: stained with Factor VIII (original magnification, 800×), Masson trichrome (original magnification, 200×), a monoclonal antibody against α-smooth muscle actin (α-SMA; brown staining; original magnification, 800×), and safranin O (red staining; original magnification, 200×). The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions


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