1. Time to Take Gout Seriously

3. Overall Program Agenda

4. Epidemiology and Pathogenesis of Gout

5. Overall Prevalence of Gout

7. Comorbidities of Gout

8. Pathophysiology of Gout

9. Hyperuricemia and Crystal Deposition

11. Natural Course of Disease

12. Conclusions

13. Guideline Recommendations for Diagnosis and Treatment of Gout

14. Key Points for Discussion

15. When to Initiate ULT

16. The Treat to Target Approach

18. Monitoring SUA Levels in Patients on ULT

19. Conclusions

20. Current and Emerging Treatment Options for Gout

21. Key Points for Discussion

22. EULAR Recommendations for ULT

23. Review of Currently Available ULT

24. Lesinurad Plus Allopurinol in Patients With Gout: CLEAR 1 and CLEAR2

25. Lesinurad Plus Febuxostat in Patients With Tophaceous Gout: CRYSTAL

26. Effect of Lower SUA on Tophi and Gout Flares: Pooled Analysis of CLEAR 1, CLEAR 2, and CRYSTAL

27. ULT in Development

29. Treating and Preventing Flares

30. Conclusions

31. Cardiovascular Risks and Complications in Patients With Gout

32. Increased Risk for CV Complications and Mortality in Patients With Gout

34. Risk for HF and Mortality Increases With Increasing SUA

35. Managing CV Risk in Patients With Gout

36. Managing CV Risk in Patients With Gout (cont)

37. Case Example: Presentation

38. Case Example: Management

39. Conclusions

40. Renal Complications in Patients With Gout

42. EULAR Recommendations for Patients With Impaired Renal Function

43. Treating Gout Patients With Renal Impairment in Clinical Practice

44. Monitoring Gout Patients With Renal Impairment in Clinical Practice

45. Case Example: Presentation

46. Case Example: Management

47. Conclusions

48. Best Practice for Managing Gout in Primary Care

49. Defining the Role of the PCP

50. Managing Patients With Gout in Primary Care

51. Barriers to Effective Management of Gout in Primary Care

52. Optimizing the Physician-Patient Relationship in Primary Care

53. When to Refer Patients With Gout for Specialty Consultation

54. Conclusions

55. Program Conclusions

56. Abbreviations

57. Abbreviations (cont)

58. Abbreviations (cont)