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Cost-Effectiveness Analysis of Afatinib versus Gefitinib for First-Line Treatment of Advanced EGFR-Mutated Advanced Non–Small Cell Lung Cancers  Christos.

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Presentation on theme: "Cost-Effectiveness Analysis of Afatinib versus Gefitinib for First-Line Treatment of Advanced EGFR-Mutated Advanced Non–Small Cell Lung Cancers  Christos."— Presentation transcript:

1 Cost-Effectiveness Analysis of Afatinib versus Gefitinib for First-Line Treatment of Advanced EGFR-Mutated Advanced Non–Small Cell Lung Cancers  Christos Chouaid, MD, PhD, Laura Luciani, PharmD, MSc, Katell LeLay, MSc, Pascal Do, MD, Jaafar Bennouna, MD, PhD, Maurice Perol, MD, PhD, Denis Moro-Sibilot, MD, PhD, Alain Vergnenègre, MD, PhD, Gérard de Pouvourville, PhD  Journal of Thoracic Oncology  Volume 12, Issue 10, Pages (October 2017) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Model outline. PF, progression-free; PD, progressive disease.
Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 First-line afatinib versus gefitinib probabilistic sensitivity analysis scatterplots of incremental costs versus incremental quality-adjusted life-years (QALYs). All common EGFR mutations (A) and del19 (B) and L858R subgroups (C). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

4 Figure 3 Acceptability curves of afatinib versus gefitinib. ITT, intention to treat. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions


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