2. sIBM: Epidemiology

3. Disease Characteristics: Distinctive Patterns of Muscle Involvement

4. Clinical Findings: Quadriceps Weakness and Wasting

5. Clinical Findings: Finger Flexion and Grip Weakness

6. Clinical Findings: Respiratory Muscle Weakness

7. sIBM: Disease Progression Over Time

8. Differential Diagnosis

9. Diagnostic Testing

10. Myositis-Specific Autoantibodies

11. Diagnostic Criteria

12. Pathological Features: Endomysial Inflammatory Infiltrates

13. Pathological Features: Invasion by Inflammatory Cells

14. Pathological Features: Rimmed Vacuoles

15. Pathological Features: Immunostaining

16. Pathogenesis Working Hypothesis: Inflammation  Degeneration

17. sIBM: Current Management Challenges

18. Causes of Death in Patients With sIBM

19. Conclusions

20. Abbreviations