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Enzymes and Proteins
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Explain Primary Structure
Order of amino acid chain
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Explain secondary structure
Folding of amino acid chain Alpha helix & beta pleated sheet Hydrogen bonding
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Tertiary Structure Specific 3D shape
Hydrophobic and hydrophillic interactions Disulphide bonds Ionic bonds
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Quaternary Structure Haemoglobin Globular protein
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Collagen Fibrous protein
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Enzymes Globular proteins Specific tertiary structure
Catalyse metabolic reactions in living organisms May be intracellular or extracellular
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Enzyme Action Specificity Active Site Lock and Key hypothesis
Induced fit hypothesis Enzyme-substrate complex Enzyme product complex Lowers activation energy
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Effects of pH
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Effects of temperature
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Effects of enzyme concentration
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Effects of substrate concentration
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Competitive Inhibitors
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Non-competitive inhibitors
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Cofactors and Coenzymes
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Metabolic Poisons Enzyme inhibitors
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Medicinal Drugs Some work by inhibiting the activity of enzymes
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