1. Scientific and Technical Department
“One World One Health”TM and the Implications for Biosafety and Laboratory Biosecurity
Joint WHO/OIE/FAO Biosafety and Laboratory Biosecurity Meeting
OIE Headquarters, Paris
30 June, 2009
Kate Glynn DVM, MPVM
Scientific and Technical Department

2. “One World, One Health”TM
2004 : Manhattan Principles of the Wildlife Conservation Society
It is clear that no one discipline or sector of society has enough knowledge and resources to prevent the emergence or resurgence of diseases in today's globalized world… Only by breaking down the barriers among agencies, individuals, specialties and sectors can we unleash the innovation and expertise needed to meet the many serious challenges to the health of people, domestic animals, and wildlife and to the integrity of ecosystems…We are in an era of "One World, One Health" (OWOH) and we must devise adaptive, forward-looking and multidisciplinary solutions to the challenges that undoubtedly lie ahead.
TM Wildlife Conservation Society

3. Human-Animal-Ecosystem Domain Interface
Treadwell, In: Achieving Sustainable Capacity for Surveillance and Response to Emerging Diseases of Zoonotic Origin: Institute of Medicine Workshop Summary. National Academies Press

4. Animal-Human-Pathogen-Ecosystem Interfaces

5. Number of EID Events per Decade by Transmission Type
EID events = classified by the temporal origin of the original case or cluster of cases that represents a disease emerging in the human population
Jones K et al. Nature, Vol 451| 21 February doi: /nature06536

6. Global distribution of relative risk of an EID event caused by zoonotic pathogens
Maps are derived for EID events caused by: a) zoonotic pathogens from wildlife and b) zoonotic pathogens from nonwildlife, and are mapped on a linear scale from green (lower values) to red (higher values).
Jones K et al. Nature, Vol 451| 21 February doi: /nature06536

7. Influenza Coordination
Contributing to One World, One Health* A Strategic Framework for Reducing Risks of Infectious Diseases at the Animal–Human–Ecosystems Interface 14 October 2008
UN System
Influenza Coordination
THE WORLD BANK
*Used with permission of the Wildlife Conservation Society

8. Contributing to One World, One HealthTM A Strategic Framework for Reducing Risks of Infectious Diseases at the Animal–Human–Ecosystems Interface
… build on the existing approaches and mandates of international institutions and other partners to form a flexible network…
…a network that is expected to be nimble enough to be able to adapt, form new coalitions, and respond rapidly to any new health emergencies
Internationally, this network would be built on a number of structures and mechanisms that have been already established by agencies such as FAO, OIE, WHO and UNICEF

9. Specific objectives and outputs Strategic Framework for Reducing Risks of Infectious Diseases at the Animal–Human–Ecosystems Interface
Develop surveillance capacity, including the development of standards, tools and monitoring processes at national, regional and global levels
Strengthen public and animal health capacity, including communication strategies to prevent, detect and respond to disease outbreaks at national, regional and international levels
Strengthen national emergency response capability, including a global rapid response support capacity
Promote inter-agency and cross-sectoral collaboration and partnerships
Control HPAI and other existing and potentially re-emerging infectious diseases
Conduct strategic research

10. OIE Listed Diseases – Multiple Species Diseases
Anthrax
Aujeszky's disease
Bluetongue
Brucellosis (B. abortus/melitensis/suis)
Crimean Congo haemorrhagic fever
Echinococcosis/hydatidosis
Epizootic haemorrhagic disease
Equine encephalomyelitis (Eastern)
Foot and mouth disease
Heartwater
Japanese encephalitis
New world screwworm (Cochliomyia hominivorax)
Old world screwworm (Chrysomya bezziana)
Paratuberculosis
Q fever
Rabies
Rift Valley fever
Rinderpest
Surra (Trypanosoma evansi)
Trichinellosis
Tularemia
Vesicular stomatitis
West Nile fever
These diseases are identified as multispecies diseases – those shown in bold have documented infections in humans and animals, and those in italics have been uncommonly documented or play a putative role in human disease

11. The Global Early Warning and Response System (GLEWS)
combines and coordinates the alert and response mechanisms of OIE, FAO and WHO
assists in prediction, prevention and control of animal disease threats, including zoonoses

13. GLEWS Zoonotic Diseases of Interest
Anthrax
Brucellosis (B. melitensis)
BSE
Crimean Congo haemorrhagic fever
Ebola virus
Foodborne Diseases
Highly Pathogenic Avian Influenza
Japanese equine encephalitis
Marburg Hemorrhagic Fever
New world screwworm
Nipah Virus
Old world screwworm
Q fever
Rabies
Rift Valley fever
Sheep Pox/Goat Pox
Tularemia
Venezuelan equine encephalitis
West Nile fever
Non-Zoonotic Diseases:
African Swine Fever, Classical Swine Fever, Contagious Bovine Pleuropneumonia, Foot and mouth disease, Peste des Petits Ruminants, Rinderpest

14. Summary – OWOH and the Implications for Biosafety and Laboratory Biosecurity
Increasing emerging diseases and increasing role of zoonotic pathogens
Fighting the disease at its source – increased handling of novel pathogens, with poorly defined zoonotic potential, at veterinary and human medicine laboratories
Focused activity in proposed “hotspots”, with fewer resources to maintain stringent biosafety and laboratory biosecurity standards
Increased referrals of “unidentified” pathogens to international reference laboratories

15. Thank you for your attention
Organisation Mondiale de la Santé Animale
World Organisation for Animal Health
Organización Mundial de Sanidad Animal
Thank you for your attention
12 rue de Prony, Paris, France - –