1. Unit 4 Part 3 Cellular Respiration: Mitochondria, Krebs & Oxidative Phosphorylation

2. Mitochondria Be able to identify: Inner membrane Outer membrane
Cristae
Matrix

3. Cellular Respiration
Location?

4. Cellular respiration The process: Reactants (inputs): Glucose & Oxygen
Products (Outputs): CO2, H2O & ATP

5. Electron Carriers in CR
NAD+  NADH
FAD+  FADH2

6. Stuff… Oxidation Reduction Means to LOSE an electron
Means to GAIN an electron
Two ways to remember: OIL RIG or LEO the lions says GER

7. Cellular Respiration
Glycolysis/Bridging Process (substrate-level phosphorylation)
Krebs Cycle/Citric Acid Cycle (substrate-level phosphorylation)
Electron Transport Chain (oxidative phosphorylation)

8. Krebs Cycle aka Citric Acid Cycle
Location--Matrix of mitochondria
Aerobic  requires O2 as final e- acceptor
Produces:
CO2 (from carbonyl)
NADH
FADH2
ATP

9. Krebs….part 1
Pay attention to what we start with & what is being made!

10. Krebs….part 2
Pay attention to what is being made!

11. Krebs….part 3
Pay attention to what is being made!

12. Krebs….part 4
Pay attention to what is being made!

15. Electron Transport Chain
Location--Membrane of cristae
Aerobic  requires O2 (final electron acceptor)
Follow the electrons—and protons!
Animation
vcell.ndsu.nodak.edu/animations/etc/first.htm

16. Oxidative Phosphorylation
Electrons power proton pumps (which are imbedded proteins)  pump H+ into intermembrane space (ETC)
Generates ATP when H+ diffuse back into matrix thru ATP Synthase (Chemiosmosis)
NAD+ powers 3 pumps  3 ATP
FAD+ powers 2 pumps  2 ATP

17. Oxidative Phosphorylation
e- transferred to oxygen through proton pumps  builds up proton gradient
Generates ATP through ATP Synthase